Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2
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How the Intestinal Peptide Transporter PEPT-1 Contributes to an Obesity Phenotype in Caenorhabditits elegans
BACKGROUND Amino acid absorption in the form of di- and tripeptides is mediated by the intestinal proton-coupled peptide transporter PEPT-1 (formally OPT-2) in Caenorhabditits elegans. Transporter-deficient animals (pept-1(lg601)) show impaired growth, slowed postembryonal development and major changes in amino acid status. PRINCIPAL FINDINGS Here we demonstrate that abolished intestinal pept...
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The abundance of the oligopeptide transporter (Pept-1) in the brush-border membrane of the intestinal epithelium is the central mechanism for regulation of transport of products of protein digestion (dipeptides and tripeptides) and peptidomimetic drugs (for example, beta-lactam antibiotics). Within the past few years, there has been substantial progress in identifying the factors controlling th...
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We present a high-level RPC architecture. Although RPC systems seem quite varied they actually share the same fundamental building blocks. We examine the operation of several technologies (e.g., SOAP/HTTP, RMIIIOP) to show what they have in common, namely four main blocks that we call PEPt: Presentation, Encoding, Protocol and transport. Presentation encompasses the data types and APIs availabl...
متن کامل1 Protein Hydrolysate - Induced Cholecystokinin Secretion from 1 Enteroendocrine Cells Is Indirectly Mediated by the Intestinal 2 Oligopeptide Transporter Pept
PROTEIN HYDROLYSATE-INDUCED CHOLECYSTOKININ SECRETION FROM 1 ENTEROENDOCRINE CELLS IS INDIRECTLY MEDIATED BY THE INTESTINAL 2 OLIGOPEPTIDE TRANSPORTER PEPT1 3 4 5 6 Alice P. Liou, Diana I. Chavez, Elvis Espero, Shuzhen Hao, Stephen A. Wank, Helen E. 7 Raybould 8 9 10 11 12 13 Department of Anatomy, Physiology, and Cell Biology 14 School of Veterinary Medicine, University of CaliforniaDavis 15 D...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 1997
ISSN: 0005-2736
DOI: 10.1016/s0005-2736(96)00234-9